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The super elongation complex drives transcriptional addiction in MYCN-amplified neuroblastoma

Resolving the lineage relationship between malignant cells and vascular cells in glioblastomas

Pax transactivation domain-interacting protein is required for preserving hematopoietic stem cell quiescence via regulating lysosomal activity

RNA helicase DHX15 exemplifies a unique dependency in acute leukemia

β-adrenoreceptor-triggered PKA activation negatively regulates the innate antiviral response

Dual-Responsive STAT3 Inhibitor Nanoprodrug Combined with Oncolytic Virus Elicits Synergistic Antitumor Immune Responses by Igniting Pyroptosis

Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance

Endocytosis triggers V-ATPase-SYK-mediated priming of cGAS activation and innate immune response