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FAM134B-mediated ER-phagy degrades APP and suppresses Alzheimer's disease pathology

Quadruple pegRNA enables programmable and efficient large genomic insertion

Reciprocal regulation of TNF receptor 1-mediated signaling and inflammatory damages by MARCH2 and USP22

Homeostatic maturation programs drive human cDC2s into a tolerogenic state

TGFβ-activated PDHB promotes mitochondrial pyruvate metabolism and contributes to human endoderm differentiation via ATP-dependent BRG1

Grhl3 Downregulation Facilitates ECM Adaptation for Fibroblast to iCM Commitment

CDK10 suppresses nucleic acid sensors-mediated antitumor immunity

ChREBP-Mediated Choline Deprivation and Chemokine Secretion Shape Tumor-Associated Macrophages to Promote Immune Evasion